Corporate Health & Wellness Specialist – PrognoHealth

Neonatal Hemoglobin Electrophoresis (Hb Electrophoresis) Test

Neonatal Hemoglobin Electrophoresis (Hb Electrophoresis) is a laboratory test used to detect and diagnose abnormal hemoglobin types in newborns. Hemoglobin is a protein in red blood cells that carries oxygen throughout the body. Abnormal hemoglobin types, such as sickle cell anemia and thalassemia, can cause serious health problems.

Pre-test preparation: No special preparation is required for this test.

Testing method: The test is typically done using a small sample of blood taken from the heel or the arm of the newborn baby. The blood sample is then placed on a gel and an electrical current is applied, which separates the different types of hemoglobin based on their electrical charge. The resulting bands on the gel are then analyzed and interpreted by a laboratory technician.

Common symptoms for prescribing this test: This test is typically ordered as part of a routine screening for newborns, especially for newborns born in regions with high prevalence of Hemoglobinopathies or if the parents have a family history of Hemoglobinopathies.


Diagnosis: The test results will indicate the presence or absence of abnormal hemoglobin types such as sickle cell anemia and thalassemia.

Reference range: The reference range for Hb Electrophoresis will depend on the specific test being used.

Normal values: A normal result will show the presence of the normal hemoglobin (HbA) and absence of abnormal hemoglobin types such as HbS, HbC and HbE. In case of abnormal result, the presence of abnormal hemoglobin types will be indicated.

It is important to consult with a doctor or healthcare professional for any questions or concerns regarding the this test or any other medical test


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