PrognoHealth – Corporate Health & Wellness Specialist
Adult Hemoglobin Electrophoresis (Hb-Elec) Test
Adult Hemoglobin Electrophoresis (Hb-Elec) test is a laboratory test that separates different types of hemoglobin present in the blood by using an electric current. It is used to detect and diagnose genetic disorders of hemoglobin such as sickle cell anemia and thalassemia.
Pre-test preparation:
No special preparation is usually required for this test.
Testing method:
- A small sample of blood is taken from a vein in the arm using a needle and syringe.
- The sample is then sent to a laboratory for analysis.
- The blood sample is applied to a gel, and an electric current is applied to the gel.
- As the current is applied, the different types of hemoglobin move through the gel at different rates, based on their charge and size, and separate into bands.
- The separated bands are then visualized and compared to a reference standard to identify the types and amounts of hemoglobin present in the sample.
Common symptoms for prescribing this test:
- Fatigue
- Weakness
- Shortness of breath
- Rapid heartbeat
- Pale skin
- Headaches
- Dizziness
- Chest pain
- Jaundice
- Splenomegaly
- Leg ulcers
- Priapism
- Aplastic crises
- Gallstones
- Avascular necrosis
Diagnosis:
The Hb-Elec test is used to help diagnose and monitor genetic disorders of hemoglobin such as sickle cell anemia and thalassemia.
Reference range:
The reference range for Hb-Elec test varies depending on the laboratory that performs the test and the patient’s age, sex, and overall health.
A normal Hb-Elec test will show primarily adult hemoglobin (HbA) with a small amount of fetal hemoglobin (HbF).
Abnormal results can show a shift in the ratio of HbA to HbF or the presence of abnormal hemoglobin such as HbS or HbC.
Normal values:
Normal values for Hb-Elec test vary depending on the lab that performed the test, but typically show primarily adult hemoglobin (HbA) with a small amount of fetal hemoglobin (HbF).
It is important to consult with a doctor or healthcare professional for any questions or concerns regarding the Hb-Elec test or any other medical test.
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