Total protein Test The total protein test is a laboratory test that measures the amount of protein in the blood. Protein is essential for many bodily functions such as maintaining healthy muscles, bones, skin, and hair, and fighting infections. There is no specific pre-test preparation required for the total protein test. The test is typically done by drawing blood from a vein in the arm and sending it to a lab for analysis. Common symptoms that may lead a healthcare provider to prescribe a total protein test include fatigue, weakness, weight loss, and swelling in the legs or abdomen. Individuals who have a history of kidney disease, liver disease, or who have a family history of protein deficiencies are at risk of having low protein levels and may need to be tested. The test is used to diagnose and monitor conditions that affect protein levels in the body such as malnutrition, liver disease, kidney disease, and certain cancers. High or low levels of total protein can indicate the presence of these conditions and monitor their progression. The reference range for total protein levels varies depending on the lab that is performing the analysis but generally, the normal range for adults is considered to be between 6 and 8 grams per deciliter (g/dL). However, it is important to consult a healthcare professional for proper interpretation of the results, as other factors such as age, sex, and other medical conditions can affect total protein levels. It’s important to note that total protein test is not a diagnostic test, it is only a screening test, and it should be used in conjunction with other diagnostic tests such as albumin, globulin, and other blood tests to diagnose the underlying condition and monitor the treatment. Additionally, a positive screening test does not confirm the presence of the underlying condition, it only indicates that there is an increased risk and a diagnostic test is needed for a definitive diagnosis.