Aspartate Aminotransferase (AST) is an enzyme that is found in several body tissues, including the liver, heart, muscles, and kidneys. The AST test, also known as SGOT (serum glutamic-oxaloacetic transaminase) test, is used to measure the level of AST in the blood, which can help diagnose liver and heart problems.

Pre-test preparation:

No special preparation is usually required for an AST test.

Testing method:

A blood sample is taken and sent to a laboratory for analysis.

Common symptoms that may prompt a healthcare provider to prescribe an AST test include:

• Jaundice (yellowing of the skin and whites of the eyes)
• Abdominal pain
• Nausea
• Fatigue
• Loss of appetite
• Dark-colored urine
• Itchy skin

Diagnosis:

Elevated levels of AST in the blood can be a sign of liver or heart problems. Liver conditions such as hepatitis, cirrhosis, and liver cancer can cause elevated AST levels. Heart conditions such as myocardial infarction (heart attack) can also cause elevated AST levels.

Reference range:

Normal values for AST levels in the blood vary depending on the laboratory, but generally range from 5 to 40 units per liter (U/L) for men and from 5 to 35 U/L for women.

It’s important to note that the test results should be interpreted in the context of the patient’s clinical presentation and other test results. A single test result should not be used as the sole basis for diagnosis and treatment decisions. A qualified healthcare professional should interpret the test results and give you a proper diagnosis. Additionally, other liver function test like ALT (Alanine Aminotransferase) should also be considered along with AST test to get a better understanding of liver function.