Tests

Bicarbonate test

Updated: Apr 13, 2026 Published: Jun 24, 2023 Medical Team 1 min read

    The Bicarbonate test is used to measure the level of bicarbonate in the blood, which is a buffer that helps maintain the body’s acid-base balance. The test is also called total CO2 test or HCO3 test.

    Pre-test preparation: No special preparation is usually required for a bicarbonate test.

    Testing method: A blood sample is taken and sent to a laboratory for analysis.

    Common symptoms that may prompt a healthcare provider to prescribe a bicarbonate test include:
    Shortness of breath
    Confusion
    Fatigue
    Nausea
    Loss of appetite
    Coma

    Diagnosis:
    Low levels of bicarbonate in the blood can be a sign of metabolic acidosis, which is a condition in which the body produces too much acid or does not get rid of enough acid.
    High levels of bicarbonate in the blood can be a sign of metabolic alkalosis, which is a condition in which the body produces too little acid or gets rid of too much acid.

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