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Alpha-Fetoprotein (AFP) Test

Updated: Apr 14, 2026 Published: May 12, 2023 Medical Team 2 min read

    Alpha-Fetoprotein (AFP) is a protein that is produced by the liver and yolk sac of a developing fetus. It is typically measured as part of prenatal screening for certain birth defects, such as neural tube defects and Down syndrome.

    Pre-test preparation: No specific preparation is usually required for an AFP test.

    Testing method: AFP test is usually done as part of a blood test. A sample of blood is taken from a vein in the arm and sent to a lab for analysis.

    Common symptoms for prescribing this test: The test is usually done as part of prenatal screening for certain birth defects, such as neural tube defects and Down syndrome.

    Diagnosis: An elevated level of AFP in the mother’s blood may indicate a neural tube defect or Down syndrome in the fetus. However, it is important to note that an elevated level of AFP does not necessarily mean that there is a problem with the fetus, as there are many other possible causes for an elevated AFP level.

    Reference range: The normal reference range for AFP levels in a pregnant woman’s blood is typically less than 2.5 ng/mL.

    Normal values:
    -AFP levels in a non-pregnant woman is usually less than 10 ng/mL.
    -Elevated levels of AFP can indicate several conditions including cancer of the testicles, ovaries, stomach, pancreas, liver or lung.
    It is important to consult with a doctor or healthcare professional for any questions or concerns regarding the Hb-Elec test or any other medical test.

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