Sickling test is a laboratory test used to diagnose sickle cell anemia, a genetic blood disorder characterized by abnormal hemoglobin molecules that can cause red blood cells to become crescent-shaped or “sickle-shaped.”

Pre-test preparation: No specific preparation is required for this test.

Testing method: The sickling test is typically performed on a sample of blood that is obtained by a finger prick or venipuncture. The blood sample is then placed in a test tube containing sodium metabisulfite, a chemical that causes the red blood cells to sickle. The test is considered positive if at least 50% of the red blood cells show evidence of sickling.

Common symptoms for prescribing this test: The most common symptoms of sickle cell anemia include anemia, fatigue, jaundice, and recurrent infections. Pain crises, also known as sickle cell crises, are also a common symptom and may occur in the bones, chest, or abdomen.

Diagnosis: A positive sickling test confirms the diagnosis of sickle cell anemia.

Reference range: The test should show at least 50% of red blood cells sickling.

Normal values: A negative sickling test indicates normal hemoglobin and the absence of sickle cell anemia.

It is important to consult with a doctor or healthcare professional for any questions or concerns regarding the this test or any other medical test